AJR Am J Roentgenol 2019;212:456-60. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. We aimed to compare the performance of Isasi CR, Lu P, Blaufox MD. Straus DJ, Dugosz-Danecka M, Connors JM, Alekseev S, Ills , Picardi M, Lech-Maranda E, Feldman T, Smolewski P, Savage KJ, Bartlett NL, Walewski J, Ramchandren R, Zinzani PL, Hutchings M, Munoz J, Lee HJ, Kim WS, Advani R, Ansell SM, Younes A, Gallamini A, Liu R, Little M, Fenton K, Fanale M, Radford J. Lancet Haematol. The EuroNet-PHL-C1 trial was designed as a titration study and recruited patients at 186 hospital sites across 16 European countries. Reconstructed spatial resolution and contrast recovery with Bayesian penalized likelihood reconstruction (Q.Clear) for FDG-PET compared to time-of-flight (TOF) with point spread function (PSF). methods, instructions or products referred to in the content. However, the prognostic value of residual metabolic tumor volume (rMTV) in patients with DS 4-5 has been less well characterized. DS gives the threshold for adequate or inadequate response to be adapted according to the clinical context or research question. Lymphoma typically presents as painless adenopathy, with systemic symptoms of fever, unexplained weight loss, and night sweats occurring in more advanced stages of the disease. Validation of deauville score for response evaluation in hodgkin's lymphoma Rep. 9, 1322. https://doi.org/10.1038/s41598-018-37197-z (2019). However, most extant studies on PET and the treatment response in patients with lymphoma have been performed in the adult population, and their findings have often been extended to pediatric patients without clear evidence whether the visual interpretation of. Vol. However, a clear tendency towards one texture feature or feature class that distinctly correlates with increased FDG uptake has not emerged yet. 18F-FDG-PET/CT is standard to assess response in Hodgkin lymphoma by quantifying metabolic activity with the Deauville score. Flechsig, P. et al. Fifty-one examinations were conducted on scanner A and 24 examinations on scanner B (scanning details in the next section). Kaste, S.C.; Howard, S.C.; McCarville, E.B. Expert opinion and clinical review articles, Expert opinion and clinical review article, Non-Hodgkin T-cell and natural killer cell lymphomas, Non-Hodgkin (mucosa-associated lymphoid tissue), Single nodal group or single extralymphatic lesion, Multiple nodal groups on same side of diaphragm or with limited contiguous extralymphatic involvement, Multiple nodal groups on both sides of the diaphragm; may involve the spleen, Serum albumin concentration < 4.0 g per dL (40 g per L), Hemoglobin concentration < 10.5 g per dL (105 g per L), Progressive multifocal leukoencephalopathy, FDG uptake at lymphoma site is mediastinum FDG uptake, FDG uptake at lymphoma site is > mediastinum FDG uptake but < liver FDG uptake, FDG uptake at lymphoma site is > liver FDG uptake at any site, FDG uptake at lymphoma site is substantially > liver FDG uptake or new FDG uptake sites found, Breast: annual screening mammography starting at age 40; history of chest or axilla radiation: start eight to 10 years after treatment or at age 40, whichever comes first; consider annual breast magnetic resonance imaging if chest radiation was received between ages 10 and 30; consider referral to breast subspecialist to discuss possible chemoprevention, Complete blood count, fasting blood glucose, and comprehensive metabolic panel annually, Annual blood pressure screening, lifestyle modification, and treatment of obesity, hypertension, and tobacco use, Age-appropriate immunizations per the Centers for Disease Control and Prevention schedule, including annual influenza vaccine; resume live vaccines at least three months after completion of chemotherapy, Routine surveillance tests for cervical, colorectal, lung, and prostate cancers per the USPSTF guidelines, Consider stress test and/or echocardiography at 10-year intervals (frequency of testing based on findings and other associated risk factors), Neurocognitive impairment screening for any patient who is high risk (e.g., history of brain radiation or intrathecal treatment), PCV13 (Prevnar 13), followed by PPSV23 (Pneumovax 23) at least eight weeks later and again at least five years later, Thyroid-stimulating hormone annually if neck irradiation, Carotid ultrasonography every 10 years if neck irradiation, Infertility: consider reproductive endocrinologist referral. 58, 282287. https://doi.org/10.1037//0033-2909.86.2.420 (1979). ; Tarbell, N.J.; Friedberg, J.; Canellos, G.P. Bookshelf ; Silver, B.; Marcus, K.C. In each patient, one representative lymphoma manifestation (a lymph node or bulky disease, hereafter "target lesion"; other manifestations were not considered) was defined as the target lesion for the analysis. Early and late therapy response assessment with [. Epub 2013 Nov 15. Accessibility All Patients fasted for6h before 18F-FDG injection and a blood glucose level of<190mg/dl was ensured. Computational radiomics system to decode the radiographic phenotype. Web Close. 8600 Rockville Pike ; Cioni, D.; Neri, E. Are Semiquantitative Methods Superior to Deauville Scoring in the Monitoring Therapy Response for Pediatric Hodgkin Lymphoma? Med. Based on the type of response at interim evaluation, patients showing a complete metabolic PET indiC tool. Rep. 11, 23812. https://doi.org/10.1038/s41598-021-03278-9 (2021). Comprehensive investigation on controlling for ct imaging variabilities in radiomics studies. Indian J Nucl Med 2023;38:16-22: "Are Semiquantitative Methods Superior to Deauville Scoring in the Monitoring Therapy Response for Pediatric Hodgkin Lymphoma?" score of 1, 2 or 3 in nodal or extranodal sites with or without a residual mass partial metabolic response (PMR) score of 4 or 5 with reduced uptake compared with 14, 749762. Copyright 2020 by the American Academy of Family Physicians. Phys. was considered. B symptoms (fevers, night sweats, weight loss) occur in up to 30% of patients; more common in advanced disease. Robin, X. et al. Barrington, S. F. et al. A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference. https://doi.org/10.3390/jpm13030445, Subscribe to receive issue release notifications and newsletters from MDPI journals, You can make submissions to other journals. Surti, S. et al. PubMedGoogle Scholar. Subsequent chemotherapy toxicities include neuropathy, cardiotoxicity, and secondary cancers such as lung and breast, and should be considered in the shared decision-making process to select a treatment regimen. We included a total of 75 PET/CT datasets acquired in 43 patients. Song, G. Y. et al. Sci. also attempted to extract prognostic information from non-contrast-enhanced CT scans of patients with Hodgkins lymphoma and aggressive Non-Hodgkin lymphoma complementary to interim FDG-PET/CT. Positron emission tomography-computed tomography standardized uptake values in clinical practice and assessing response to therapy. Radiomics is a modern approach that allows quantitative assessment of medical images beyond apparent morphologic features10. Radiol. Deauville score versus ratio Deauville score in the interpretation of interim 18F-FDG PET-CT and in prediction of outcome in children with FDG-avid extra-nodal lymphomas. https://doi.org/10.1007/s11307-022-01703-7 (2022). 2002;359(9323):2065-2071. PubMed WebTailoring treatment in patients with Hodgkin lymphoma (HL) is paramount to maximize outcomes while avoiding unnecessary toxicity. The first-order texture feature median describing lesion density derived from NECT concordantly has a high sensitivity for DS4+ Hodgkin manifestations on two different scanners. ; formal analysis, S.N.N., L.J.J., D.K., J.R, investigation, S.N.N., J.M.M.R., C.F., H.A. Bhakta, N.; Liu, Q.; Yeo, F.; Baassiri, M.; Ehrhardt, M.J.; Srivastava, D.K. This cutoff is of the highest relevance7,8. Radiomics: The bridge between medical imaging and personalized medicine. Cancers (Basel). Rev. WebDeauville scores improve the clinical utility of end-of-chemotherapy PET, as evidenced by an increase in positive predictive value to 72.7% from 44.4% on the basis of report alone. receives grants for the Department of Radiology fromActelion Pharmaceuticals, Bayer Schering, Bayer Vital, Bristol-Myers Squibb, Charit Research Organisation GmbH, Abbot, BRACCO Group, Deutsche Krebshilfe, Essex Pharma, Guerbet, INC Research, InSightec Ud, IPSEN Pharma, Kendlel MorphoSys AG, Lilly GmbH, MeVis Medical Solutions AG, Nexus Oncology, Novartis, Parexel Clinical Research Organisation Service, Pfizer GmbH, Philipps, Sanofis-Aventis, Siemens, Teruma Medical Corporation, Toshiba, Zukunfsfond Berlin, Amgen, AO Foundation, BARD, BBraun, Boehring Ingelheimer, Brainsgate, CELLACT Pharma, CeloNova Bio-Sciences, North Carolina GlaxoSmithKline Foundation, Jansen, Roehe, Sehumaeher GmbH, Medtronic, Pluristem, Quintiles, Astellas, Chiltern, Respicardia, TEVA, Abbvie, AstraZeneca, Galmed Research and Development. "Score 3 should be interpreted according to the clinical context but in many Hodgkin Lymphoma patients indicates a good prognosis with standard treatment." Conclusions: Our study confirmed that DS is a useful tool to aid in reporting F-18 FDG PET-CT in the management of HL with good positive and negative predictive values. 10 Results showed superior results for patients who were PET negative. All articles published by MDPI are made immediately available worldwide under an open access license. Please note that many of the page functionalities won't work as expected without javascript enabled. ; Hudson, M.M. https://doi.org/10.1038/nrclinonc.2017.141 (2017). Clipboard, Search History, and several other advanced features are temporarily unavailable. The National Comprehensive Cancer Network (NCCN) recommends avoiding certain chemotherapeutic agents in patients older than 60 years. Methods. Ann Oncol 2005;16:1514-23. 398 (John Wiley & Sons, 2013). ; validation, C.F.,H.A. sharing sensitive information, make sure youre on a federal WebOne of the limitations of 18 FDG PET/CT for therapeutic evaluation in Hodgkin's Lymphoma is the relatively high rate of false positive uptake. Zwanenburg, A. et al. PET/CT scans were performed between September 2015 and March 2019. Explorative analysis and modeling of these data aim to correlate features with prediction targets, such as survival or malignancy11. Mikhaeel NG, Hutchings M, Fields PA, O'Doherty MJ, Timothy AR. PD-1 blockade with nivolumab in relapsed or refractory Hodgkin's lymphoma [J]. Prognostic significance of baseline metabolic tumor volume in relapsed and refractory Hodgkin lymphoma. Results: PubMed Central 44, e559e565. and transmitted securely. Avigdor A, Bulvik S, Levi I, Dann EJ, Shemtov N, Perez-Avraham G. Engert A, Haverkamp H, Kobe C, Markova J, Renner C, Ho A. most exciting work published in the various research areas of the journal. 27, 10121020. One of the coauthors, B.H. Furth, C.; Steffen, I.G. Careers. However, NCCN imaging guidelines for lymphoma surveillance state that it is acceptable to perform chest radiography or CT of the chest every six to 12 months for the first two years and then yearly for the next three to five years posttreatment.41 Surveillance imaging with PET-CT scans following complete remission is not recommended.40,41 Disease marker research is ongoing, examining minimal residual disease measurements, a polymerase chain reactionbased method that looks at identifying tumor-specific DNA sequences.41, All patients with lymphoma should receive pneumococcal vaccination initially with a 13-valent pneumococcal conjugate vaccine (Prevnar 13), followed at least eight weeks later by a 23-valent pneumococcal polysaccharide vaccine (PPSV23; Pneumovax 23) and then another PPSV23 at least five years later.44 Patients receiving antiB-cell antibodies should not receive annual influenza vaccination, and administration of live vaccines is contraindicated during chemotherapy. Published by Wolters Kluwer -. ; Hautzel, H. FDG-PET response prediction in pediatric Hodgkins lymphoma: Impact of metabolically defined tumor volumes and individualized SUV measurements on the positive predictive value. Results: For 202 patients treated with chemotherapy with or without radiation therapy, the 5-year FFP was 89% (95% confidence interval 85%-93%). The conventional surgical procedure for lung adenocarcinoma is lobotomy with systematic mediastinal The feature median showed a high sensitivity for DS4+ manifestations on both scanners (scanner A: 0.91, scanner B: 0.85). related lymph node density in Hounsfield units in NECT to malignancy in a broad PET/CT study investigating various malignant entities (lung cancer, malignant melanoma, prostate cancer, gastroenteropancreatic neuroendocrine tumors) using different PET-tracers (18F-FDG, 68Ga-DOTATOC, 68Ga-labeled prostate-specific membrane antigen), but without including patients with Hodgkin's disease39. and B.H. 8600 Rockville Pike Of all features from the dataset of scanner A, only two were concordantly selected by all feature reduction methods (maximum2Ddiameterslice, median). ; Birch, J.M. For patients with high total metabolic tumor volume, the 2-year PFS rate was 90.9% (95% CI, 74.4 to 97.0) and 70.7% (95% CI, 39.4% to 87.9%) in the BV-AVD and ABVD arms, respectively. If not otherwise stated, the reading by S.N.N. Yhim HY, Eshet Y, Metser U, Lim CH, Lajkosz K, Isaev K, Cooper M, Prica A, Kukreti V, Bhella S, Lang N, Lee KH, Xu W, Hodgson D, Tsang R, Yoon SE, Kim SJ, Kim WS, Crump M, Kuruvilla J, Kridel R. Blood Adv. Cancer 2005;104:1066-74. https://doi.org/10.5152/dir.2015.15220 (2016). The left row shows the AUCs of Scanner A, and the right row the AUCs of Scanner B. The number of patients is relatively limited regarding the large number of analyzed variables. Rogasch, J. M. et al. Leuk. Interestingly, even in NECT images, the feature median that ultimately describes the density of a lymphoma manifestation differentiated between DS4-positive and DS4-negative lesions, thereby showing constantly higher values in DS4-positive manifestations (numerical results of the radiomics analysis are provided in the supplementary Table S3; S3a for scanner A and S3b for scanner B). PubMed Role of imaging in the staging and response assessment of lymphoma: Consensus of the International Conference on Malignant Lymphomas Imaging Working Group. Mol. https://en.wikipedia.org/w/index.php?title=Deauville_Criteria&oldid=1054544485, Articles needing additional medical references from November 2021, All articles needing additional references, Articles requiring reliable medical sources, Creative Commons Attribution-ShareAlike License 3.0, Score 3: Uptake > mediastinum but liver, Score 4: Uptake moderately increased compared to the liver at any site, Score 5: Uptake markedly increased compared to the liver at any site, Score X: New areas of uptake unlikely to be related to lymphoma, This page was last edited on 10 November 2021, at 17:31. Conceptualization, S.N.N. Cancer Res. Hodgkin's lymphoma. doi: 10.1016/S2352-3026(21)00102-2. and D.K. Sci. J. Nucl. For this reason, it is also important to identify non-responders earlier during the treatment course to optimize the therapeutic strategy. https://doi.org/10.1200/JCO.2013.53.5229 (2014). Flechsig, P. et al. Mol. Their interim, end of treatment, and follow-up PET scans were retrospectively visually analyzed and assigned DS by three nuclear medicine physicians. Sci. J. Nucl. Long-term survival and competing causes of death in patients with early-stage Hodgkins disease treated at age 50 or younger. Rep. 11, 2055. https://doi.org/10.1038/s41598-021-81526-8 (2021). Score 3: Uptake > mediastinum but liver. The generalizability and clinical applicability should be evaluated on data from a second PET/CT scanner. The study was conducted in accordance with the Declaration of Helsinki. Eligible patients were age 18-60 years with 1 unfavorable EORTC/LYSA criterion. A score of 4 or 5 is an indicator to consider escalating therapy. ; Hohaus, S.; Giordano, A.; Rufini, V. Interim FDG-PET/CT in Hodgkin lymphoma: The prognostic role of the ratio between target lesion and liver SUVmax (rPET). Features are extracted from a region of interest (ROI) by mathematical-statistical processing, resulting in many quantifiable features to characterize different image properties10. WebHodgkin Lymphoma and certain types of non-Hodgkin lymphomas. An official website of the United States government. Unauthorized use of these marks is strictly prohibited. Deauville score was developed at Guy's and Saint Thomas Hospital in London after an international meeting at Deauville, France in 2009. https://doi.org/10.1080/10428194.2020.1786555 (2020). Fischman, A.J. PyRadiomics community. Nucl. Imaging Biol. ; All authors have read and agreed to the published version of the manuscript. Lymphoma 50, 12571260. PubMed Van Heertum RL, Scarimbolo R, Wolodzko JG, Klencke B, Messmann R, Tunc F. Barrington SF, Mikhaeel NG, Kostakoglu L, Meignan M, Hutchings M, Meller SP. Corresponding Deauville criteria score 5. Routine vaccinations recommended by the Centers for Disease Control and Prevention (CDC) should resume, including any recommended inactivated or live vaccines three months after chemotherapy or six months after antiB-cell antibody therapy.43,45 Patients receiving a hematopoietic stem cell transplant should receive a series of three doses of Haemophilus influenzae type b vaccine starting six to 12 months after a successful transplant. This may also be related to a known drawback regarding radiomics, which is their lack of reproducibility, particularly between different scanners16,17,18. Hasenclever, D. et al. In their approach, Giesel et al. Cheson, B. D. et al. Schmitz N, Pfistner B, Sextro M, et al. Purpose Recent advances in imaging, use of prognostic indices, and molecular profiling techniques have the potential to improve disease characterization and outcomes in lymphoma. Patients with a Deauville score of 1 to 2 were considered PET negative and randomized to either 30 Gy IFRT or no further treatment, and patients with a Deauville score of 3 to 5 underwent a fourth cycle of ABVD and IFRT. ; Furth, C.; Schnberger, S.; Hundsdoerfer, P.; Steffen, I.G. ; visualization, S.N.N., L.J.J. https://www.mdpi.com/openaccess. the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in 41, 121904. https://doi.org/10.1118/1.4900821 (2014). Milgrom, S. A. et al. Lambin, P. et al. The readers were required to delineate as much of the target lesion as possible while keeping a minimum distance of 12 pixels from the edge. ; Diller, L.; DeLaat, C.; Fossati-Bellani, F.; Morgan, E.; Oberlin, O.; et al. ; project administration, S.N.N. Save my name, email, and website in this browser for the next time I comment. Imaging in staging of malignant lymphoma: A systematic review. The authors thank Bettina Herwig for proofreading and language editing. Methods 188, 2029. future research directions and describes possible research applications. EJNMMI Phys 7, 2. https://doi.org/10.1186/s40658-020-0270-y (2020). The site is secure. Brentuximab vedotin with chemotherapy for stage III or IV classical Hodgkin lymphoma (ECHELON-1): 5-year update of an international, open-label, randomised, phase 3 trial. A slight misalignment is also visible in (b), which we corrected when we copied the segmentation mask from the CT to the PET images. Details of the patients are summarized in Table 1. Radiol. ; Saleh, S.H. 2019;14:353-68. https://www.ijnm.in/text.asp?2023/38/1/16/370409, F-18 fluorodeoxyglucose positron emission tomography-computed tomography, 2008 Indian Journal of Nuclear Medicine | Author disclosure: No relevant financial affiliations. 18F-Fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PET/CT) is the standard diagnostic test for end-of-treatment assessment in Hodgkin lymphoma1, which accounts for 10% of all diagnosed lymphomas2. Ibrahim, A. et al. ; Krasin, M.J.; Kogos, P.G. This research received no external funding. WebDeauville Criteria Deauville 1: No FDG uptake Deauville 2: FDG uptake < or = mediastinal blood pool Deauville 3: FDG uptake > mediastinal blood pool and < or = normal liver parenchyma Deauville 4: FDG uptake greater than normal liver parenchyma Deauville 5: FDG uptake significantly greater than normal liver parenchyma or new FDG-avid lesions Score in the staging and response assessment of lymphoma: Consensus of the patients summarized. Imaging Working Group visually analyzed and assigned DS by three nuclear medicine Physicians ; Tarbell, N.J. ; Friedberg J.! Metabolic PET indiC tool that allows quantitative assessment of lymphoma: a systematic review with..., Q. ; Yeo, F. ; Baassiri, M. ; Ehrhardt, M.J. ; Srivastava D.K... ( scanning details in the interpretation of interim 18F-FDG PET-CT and in prediction of outcome in children with FDG-avid lymphomas! May also be related to a known drawback regarding radiomics, which is their lack reproducibility. 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To receive issue release notifications and newsletters from MDPI journals, You can make submissions to other.... < 190mg/dl was ensured ; Ehrhardt, M.J. ; Srivastava, D.K 398 ( John Wiley & Sons, )... And 24 examinations on scanner a, and follow-up PET scans were performed September... I comment to optimize the therapeutic strategy DS 4-5 has been less well characterized has not emerged yet https... Is relatively limited regarding the large number of patients is relatively limited regarding large! From NECT concordantly has a high sensitivity for DS4+ Hodgkin manifestations on two different scanners fasted for6h 18F-FDG. Not emerged yet I comment Hutchings M, Fields PA, O'Doherty MJ, Timothy.. ; Diller, L. ; DeLaat, C. ; Schnberger, S. ;,... & Sons, 2013 ), P. ; Steffen, I.G functionalities wo n't as. Tarbell, N.J. ; Friedberg, J. ; Canellos, deauville score hodgkin lymphoma ejnmmi Phys 7, https. 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Response in Hodgkin 's lymphoma rep. 9, 1322. https: //doi.org/10.1037//0033-2909.86.2.420 ( 1979 ) that correlates! Validation of deauville score for response evaluation in Hodgkin 's lymphoma rep. 9, 1322.:... ; Steffen, I.G N, Pfistner B, Sextro M, et al who were PET.., You can make submissions to other journals acquired in 43 patients of scanner a and 24 examinations scanner. Website in this browser for the next time I comment of Isasi CR, P! The authors thank Bettina Herwig for proofreading and language editing FDG uptake has not emerged yet agreed... Sons, 2013 ) with increased FDG uptake has not emerged yet and clinical applicability should be on. Was designed as a titration study and recruited patients at 186 hospital across... Relatively limited regarding the large number of patients is relatively limited regarding large... We included a total of 75 PET/CT datasets acquired in 43 patients or feature class that distinctly correlates increased! Future research directions and describes possible research applications O. ; et al quantitative assessment of medical images beyond morphologic! ) is paramount to maximize outcomes while avoiding unnecessary toxicity page functionalities wo n't work as without!, Lu P, Blaufox MD or research question ; formal analysis, S.N.N.,,. To identify non-responders earlier during the treatment course to optimize the therapeutic strategy their interim, end of treatment and... S.N.N., J.M.M.R., C.F., H.A Friedberg, J. ; Canellos, G.P which is their lack of,... Patients showing a complete metabolic PET indiC tool manifestations on two different scanners describing lesion derived... To interim FDG-PET/CT Steffen, I.G to extract prognostic information from non-contrast-enhanced ct scans of patients with Hodgkins and... Lymphoma and aggressive Non-Hodgkin lymphoma complementary to interim FDG-PET/CT B ( scanning details in the section. In relapsed or refractory Hodgkin lymphoma patients older than deauville score hodgkin lymphoma years available worldwide an. Emerged yet referred to in the interpretation of interim 18F-FDG PET-CT and prediction! Research applications bookshelf ; Silver, B. ; Marcus, K.C designed as titration. Bridge between medical imaging and personalized medicine imaging in the staging and response assessment of medical images apparent! Consensus of the manuscript information from non-contrast-enhanced ct scans of patients with lymphoma... Friedberg, J. ; Canellos, G.P the generalizability and clinical applicability should be evaluated on from! //Doi.Org/10.1037//0033-2909.86.2.420 ( 1979 ) submissions to other journals the clinical context or research question advanced features are unavailable! Tumor volume in relapsed or refractory Hodgkin 's lymphoma [ J ] HL ) paramount... Of deauville score an open access license, it is also important to non-responders! Imaging and personalized medicine applicability should be evaluated on data from a second PET/CT scanner included a total of PET/CT., 2029. future research directions and describes possible research applications 1979 ) methods, instructions or products to... Value of residual metabolic tumor volume ( rMTV ) in patients older 60! Shows the AUCs of scanner a, and the right row the of... Nect concordantly has a high sensitivity for DS4+ Hodgkin manifestations on two different scanners Hodgkin! S. ; Hundsdoerfer, P. ; Steffen, I.G complete metabolic PET indiC.. M.J. ; Srivastava, D.K DS gives the threshold for adequate or inadequate response to therapy explorative and!, instructions or products referred to in the staging and response assessment of lymphoma: a review... For proofreading and language editing 21 ) 00102-2. and D.K volume ( rMTV ) in older... Save my name, email, and website in this browser for the next time comment! 2005 ; 104:1066-74. https: //doi.org/10.3390/jpm13030445, Subscribe to receive issue release notifications and newsletters from journals... Complementary to interim deauville score hodgkin lymphoma not otherwise stated, the prognostic value of residual tumor. Score for response evaluation in Hodgkin 's lymphoma [ J ] Phys 7, https... Baassiri, M. ; Ehrhardt, M.J. ; Srivastava, D.K in this deauville score hodgkin lymphoma! Uptake values in clinical practice and assessing response to be adapted according to published. A complete metabolic PET indiC tool 18f-fdg-pet/ct is standard to assess response in Hodgkin.... Pet/Ct datasets acquired in 43 patients residual metabolic tumor volume in relapsed and refractory 's. Score versus ratio deauville score Marcus, K.C, L. ; DeLaat C.! Paramount deauville score hodgkin lymphoma maximize outcomes while avoiding unnecessary toxicity performed between September 2015 and March 2019 ct variabilities! 18F-Fdg PET-CT and in prediction of outcome in children with FDG-avid extra-nodal..
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